Effects of Persistent and Bioactive Organic Pollutants on Human Health
Thus, fruits, vegetables, products of terrestrial animal origin, cereals, and other food items are regulated for their content in pesticides. However, levels of pesticides are still unregulated in fish and seafood in the EU.
Similarly, there are still no maximum limits for PCBs in marine food. Because seafood represents one of the main sources of human exposure to POPs, and that POPs contribute to metabolic diseases, policy makers and stakeholders should urgently regulate and diminish the concentrations of POPs in seafood to protect the general population. Indeed, recent studies have reported an association between fish and seafood intake and type 2 diabetes in humans [ 97 - 99 ], and possible connection between farmed Atlantic salmon and the epidemic of type 2 diabetes has been suggested [ ].
Such derogations likely rose from the fact that background contamination of certain foodstuffs is already very high -mainly because of human pollution- and that keeping maximum dioxins and dl-PCBs levels similar in all food products would result to declare considerable part of our present food supply unfit for human consumption [ 68 ].
Unfortunately, this strategy is not aimed to reduce human exposure to POPs and raise serious questions about the effectiveness of EU regulations to protect consumers. The global prevalence of metabolic diseases like obesity and type 2 diabetes, and its colossal economic and social costs represent a major public health issue for our societies. There is now solid evidence demonstrating the contribution of POPs, at environmental levels, to metabolic disorders. Thus, human exposure to POPs might have, for decades, been sufficient and enough to participate to the epidemics of obesity and type 2 diabetes.
Furthermore, POP regulation in food products should be harmonized and re-evaluated to better protect consumers. Neglecting the novel and emerging knowledge about the link between POPs and metabolic diseases will have significant health impacts for the general population and the next generations. JR has been working on environmental factors linking to obesity and type 2 diabetes.
During the last 5 years, his research studies have focused on environmental pollutants, and he demonstrated, for the first time, the causal role of POPs in the development of metabolic disorders. I am grateful to my international and national collaborators, as well as the Research Council of Norway for financial support National Center for Biotechnology Information , U.
BMC Public Health. Published online Apr Author information Article notes Copyright and License information Disclaimer. Corresponding author. Received Nov 15; Accepted Apr This article has been cited by other articles in PMC. Abstract Background Persistent organic pollutants POPs are hazardous chemicals omnipresent in our food chain, which have been internationally regulated to ensure public health. Discussion There is mounting scientific evidence showing that current POP risk assessment and regulation cannot effectively protect humans against metabolic disorders.
Summary The general population is exposed to sufficient POPs, both in term of concentration and diversity, to induce metabolic disorders. Background The incidence of obesity and diabetes has dramatically increased worldwide. Main limitations of current risk assessment on POPs in relation with metabolic disorders 1 TEQ and the concept of additive toxic effects. Open in a separate window. Figure 1. Inconsistency of POP regulation in animal food products: the case of marine food The omnipresence of POPs in animal food products has led international and national authorities to set up maximum limits.
Summary The global prevalence of metabolic diseases like obesity and type 2 diabetes, and its colossal economic and social costs represent a major public health issue for our societies. Competing interests I have no competing interests to declare. Acknowledgements I am grateful to my international and national collaborators, as well as the Research Council of Norway for financial support National, regional, and global trends in body-mass index since systematic analysis of health examination surveys and epidemiological studies with country-years and 9.
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Effects of Persistent and Bioactive Organic Pollutants on Human Health.
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Carpenter DO, ed. Background: Female reproductive system perturbations may decrease a woman's likelihood of conceiving and carrying her baby to term, influence the future life course of a viable infant, and may also reflect and have an impact on her own gynecological and general health and well-being. This chapter surveys effects of persistent organic compounds POCs and other less persistent but often pervasive bioactive organic compounds BOCs on these health outcomes. Objectives: To present an overview that highlights evidence gathered from studies and reviews, and to provide readers with background to interpret results of future studies.