Solingers Search (Compound Series Book 1)

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Contents

  1. Toward a New Social Contract in China: Overcoming the Legacy of the Old Regime
  2. Author's note
  3. Solinger's Search (Compound Series)
  4. solinger-s-search-compound-series-bookdoc - Google Документи
  5. Introduction

Thomas Kelsy. Eligha Moras. Edmon Maning. William Line. Samuel Line. George Miles. Danniel Arnold. John More, Tych Rose. Cobe Lincicom. Jerimiah Meek. Thomas Keley, Senr. Thomas Umphras. Philip Fox". Daniel Arnold, Senr. Benjamin Danels. Thomas Hill. John lowrey. Samuel McCray. John Gooding. Nathan Meek. Hugh Kee. Miles haton. Alexander Jackson. Nathan Kelley. Elijah Mills. Philip Vervile. Reuben Ross. Paul Brown. Given under my hand this 5th Day of March, I do hereby Certify that John Broadford hath served his tour of melitia Duty in My company and is hereby Dis- charged given under my hand this 2d Day of April, Cornelius Miller, absent.

Henry Dickerson. Gideon Dickerson. John Lindsly. John Guin. Zenos Lindsly. Abraham Fordice. Jacob Whosong. George Atkinson yet 1st. Timothy Ryon. Caleb Dtlle. Hath way. George Atkinson 2d. Eben'r Goble. Patrick Alison. Francis Grifflng. Daniel Axtell. James Guffy. Isaac McVae. Stephen Carter. Stephen Sanders.

Benj'm Goble. Danil Parkhurst James Johnson. Israel Dille. Noah Cook. Ebenezar Orsborn. Moses Wiliams. Jessee Bane. John Ryon. Daniel Vears. Joseph Col. Coonrod Whosong. Joseph Lindsly. Jacob Whosong, Junr. Ben'm Frazee. Jabez Baldwin. Daniel Dod.

Toward a New Social Contract in China: Overcoming the Legacy of the Old Regime

Ellis Bare. Luis Rite. Isaac Bane. Andrew Sheard. Completed this Eighth day of April by me. Andrew Farley. Jacob Stall. L Andrew Cox. James Meligin. John Line. John Mismore. Richard Hardusty. Fredrick Arnolt. Wiliam Jones. Thomas Fowler. Mical Cox, Ser.

John Hegle, Christopher Gayman. Henry Fix. Joseph Llnlcom. Soloman Grooms. Thomas Kelsey. Calip Linicom. John Wright. William Grooms. Phinias McCray. Daniel Arnold. Jeremiah Meek. Thomas Kelsy, Sen. Philip Fox. John Lowrey. John Goodwine. Nathon Meek. Elisha Morras. James Wright. John Briont. William 'Line. John More. Tych Rose. Daniel Gayman. Tebias More. Myls Heaton. Naihon Kelley. Giving under my hand. Mic'l Cox. James Miligan. And'w Kee. Frederick Arnold, Jno. Line, Senr. Given under my hand this 25th Day of S-pr.

Hause, Jno. Ross, Jno. Martin, Levan Timmons, Jno. Given under my hand this 25th Day of Sept. Lieut Colonel. David Phillips. John Small. Isaac W HI tarns, nominated,. July 7th, Corn's made out and dated 1st day of May, John Fee. Stephen Hyles. Francis Fort Thos. Joseph Archer. Nathan Hughes. Arthur Ingram. Philip Newlan. Ezekiel Morris. Simeon Archer.

Reinhart Jacob Sellers. Hezekiah Stuart. Henry Hufman. Sebastian Sroufe. Barnet Reinhart. David White. Nott 2— Vol. II— 6th Ser. Joseph Reinhart. John Jones. Itolin Hughes. Leonard Sellers. John Hath way. Clifton Bower. Petter Delay. Elisha Wiley. Earnet Eagon. John Guthrey. Elizear Clegg.

Gideon Long. Ess Davis. John Closson. Evans, Junr. Noah Long. Charles Scobey. Isaac Bozorth. David Flowers. Augustian Dilenger. Jams Long. John Long. Zebidee Lee. John Six. Nathan Currey. Charles McDowel. Solomdh Hobbs. Francis Hannah. Peter Yoho. David Long. Henry Baker. Michael Swope. Eliel Long. Henry Yoho. Aaron Jenkins. Elias Stone. Jeremiah Williams. Marthew gray. Joseph Mills. John Gray.

Robert timmons. Jacob Rush. Benjamin ginnings. Ebenezer brown. Jeames Moris. Benjamin Stits. William lee. Jeams bell. John Mills. Jacob Smitlte. Elijah Stits. William hartley. Silas Crane. Rubin purkins. Samuel 1 house. Amos Leonard. John Raws. John Martan. Eleven timons. William Wright. Nathanell Bell. William Rusk. Samuell Seals. John Veach. John Makkinea. Elishea purkens. Jeams guner. Jeams parker. John Casteel. Ziba lenard. Abner brown. Ignasea Ross, oldrage Chides ter. John oldrage. Joseph Steward. Islah hog. Jeams Hook. Louis Martain. Jobe Walton.

Jeorge hoge. Davis Jennings. Cobus Lincicom. Levi harod. Abell bell. Robert Ross. Willan Ross. Realph Smith. David ginings. Amus Lenard. Andrew Grey. Stites Compy. Marshel, Lieut. John Wagoner's company in my Battalion deserted ye 16th of October Last the next Day after they Entr'd and I de- sire you to Advertise and apprehend the said James Butler and Edward Mitchel and send them to campe under guard.

I am Sir Your Humble Se't. To Lt. Jacob Morgan. William Pollock. Thomas Parkeson. Decemb'r 24th, Joseph Beelor. Francis Dunlavien. James Brakenridge. William Armstrong. Andrew Crawford. David Smith. Samuel Thompson. Benjamin Coe. Alexander Twaddle. Hezekiah Allison. John Frew. James Sharp. Moses Coe.


  1. Money, Finance and Empire: 1790-1960: Volume 15 (Economic History)?
  2. Robinson Crusoe (Spanish Edition).
  3. MY SMALL PART!
  4. Heavenly Nugget Poems Ninth edition (The Treasury of Clyde Parker Jr.).
  5. Thomas F. Remington.

James Lowry. Elisha Vezee. Josias Crawford. William Love. James Lowrey. Alexander Frew. John Simson. James Power. Francis Morrison. John Shannon. Daniel Sweringen. Anthony Boley. John Duglas.


  1. Akteure der Umweltpolitik (German Edition).
  2. See a Problem?.
  3. Until the Last Spike, the Journal of Sean Sullivan, a Transcontinental Railroad Worker, Nebraska and Points West, 1867 (My Name Is America);
  4. Your Family Doctor to High Blood Pressure: Diagnosis and Prevention, Medicines, Self-Management.
  5. How to Kill a Consultant.
  6. 2! Signs and Coincidences from God!
  7. Slavery in Massachusetts.

David Coin. Aaron Barker. Humphrey Orr. Charles Morgan. Richard Crooks. James Hurley. James Henry. Henry Crague. Jacob Long. Thomas Sweringin. John Patterson. Nathaniel Blackmore. Cornelias Mannon. John Gardner. Thomas Mullin. Antony Dunlavlen. John Dicson. Francis Runnon. William Cammel. Henry Noble. Henry Potter. James Eliot.

George Seakman. Jacob Fite. Zadok Wright. Thomas Lap sly. Henry Kuykindall. Jacob Rob. Jam's Sparks. Samuel Fauster. Jam's Watson. Robert Eostub. Jacob Beams. John Forgy. Joseph Heth. Tobias Woods. John Barracman. John Trombo.

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Gilbert Fite. James Colter. John Chaimbers. Abrah Willson. Jam's Wallas. Abrah Kuyhendall. John McNulty. Silas Dexter. John Heth. John Persol. John Say. Benj'n Sweet. Adam Sligh. John Reed. James Eguue. William Lemaster. Wil'm Elliot. John Consauly. Adam McFarrin. John Malady. John Woods. Oliver Eliot. John Wallas. John Kincaid. John Shields. David Coot. James Kildue. John Stevlnson. Isr J Med Sci.

Symptomatic and asymptomatic accessory navicular bones: findings of Tcm MDP bone scintigraphy. Clin Radiol. Study title: Chronic recurrent multifocal osteomyelitis CRMO with symmetric involvement of both femora: X-ray, bone scintigram, and MR imaging findings in one case. Strobel K. J Mag Reson Imaging ; Study title: bay b mg vaginal tablet: efficacy and tolerance of bay b mg vaginal tablet as single or one day therapy of vaginal yeast infections.

Study title: effectiveness and tolerance of bay b 2 per cent vaginal cream on therapy for 3 days compared to therapy for 7 days with econazole 1 per cent vaginal cream gyno-pevaryl cream. Study title: Efficacy and tolerability of clotrimazole vaginal cream 10 in comparison with clotrimazole vaginal tablets mg after a single application in patients with vaginal yeast infections. Study title: efficacy and tolerability of clotrimazole vaginal tablets mg galenic formulation with lactic acid in the 6-day-therapy in vaginal candida-infections. Study title: efficacy and tolerance of two galenical product formulations of canesten vaginal tablets containing mg of the active ingredient clotrimazole after a single administration to patients with vaginal yeast infections.

The treatment of diffuse undifferentiated non-Hodgkin's lymphoma in children: the Childrens Cancer Study Group experience. Study title: Jurgens-H, Distler-W. Puberty development and gonad function after treatment with cytostatics during childhood. Jurgens-H, Distler-W. Survival and late effects in medulloblastoma patients treated with craniospinal irradiation under three years old. Chemotherapy of malignant brain tumors in children. Study title: Chirurg. Study title: Clin Nucl Med. Thymic uptake of radiopharmaceuticals. Study title: Diabetes Care. Blood pressure does not rise before the onset of microalbuminuria in children followed from diagnosis of type 1 diabetes.

Oxford Regional Prospective Study Group. Study title: Endocr Pract. Comment in: Endocr Pract. Study title: Epilepsia. Neuropsychological findings in Rolandic epilepsy and Landau-Kleffner syndrome. Pulmonary gas exchange and ventilatory responses to brief intense intermittent exercise in young trained and untrained adults. Study title: Eur J Haematol. Extratemporal hypometabolism on FDG PET in temporal lobe epilepsy as a predictor of seizure outcome after temporal lobectomy. Epub Jan 9. Epub Mar Epub Mar 9. Epub Feb 5. Response prediction by FDG-PET after neoadjuvant radiochemotherapy and combined regional hyperthermia of rectal cancer: correlation with endorectal ultrasound and histopathology.

Epub Aug J Oral Maxillofac Surg. Study title: Allograft bone in the treatment of desmoplastic fibroma. A case report. Clayer M, Oakeshott R. Study title: Camurati-Engelmann disease: contribution of bone scintigraphy to genetic counseling. Radionuclide bone scanning of osteosarcoma: falsely extended uptake patterns. Study title: J Pediatr Hematol Oncol. Study title: Jpn Circ J. Myocardial blood flow and metabolism in patients with hypertrophic cardiomyopathy--a study with carbon acetate and positron emission tomography.

Study title: Klin Padiatr. Study title: Leuk Lymphoma. Positron emission tomography PET for staging and evaluation of response to treatment in patients with Hodgkin's disease. FDG-PET is superior to gallium scintigraphy in staging and more sensitive in the follow-up of patients with de novo Hodgkin lymphoma: a blinded comparison.

Comment in:Leuk Lymphoma. Randomized comparison of consolidation radiation versus observation in bulky Hodgkin's lymphoma with post-chemotherapy negative positron emission tomography scans. Leuk Lymphoma. Study title: Lung Cancer. Study title: Investigation of the effectiveness and tolerance of a single administration of clotrimazole vaginal tablet of mg in cases of vaginal candida infection in comparison with a 6-day theraphy with clotrimazole vaginal tablets of mg.

Study title: Investigation of the effectiveness and tolerance of a single administration of clotrImazole vaginal tablet of mg in cases of vaginal candida infection in comparison with a 6-day theraphy with clotrimazole vaginal tablets of mg. Study title: Coze C et al. NB87 induction protocol for stage 4 neuroblastoma in children over 1 year of age: a report from the French Society of Pediatric Oncology. Clin Oncol. Study title: Crist W et al. The Third Intergroup Rhabdomyosarcoma Study. Study title: Crist WM et al.

Intergroup rhabdomyosarcoma study-IV: results for patients with nonmetastatic disease. Study title: Cushing B et al, Randomized comparison of combination chemotherapy with etoposide, bleomycin, and either high-dose or standard-dose cisplatin in children and adolescents with high-risk malignant germ cell tumors: a pediatric intergroup study—Pediatric Oncology Group and Children's Cancer Group , J Clin Oncol.

Cunningham B. Cosmetic Dermatology Cosmet. Study title: Young patient trabeculectomy: Assessment of risk factors for failure. Sturmer J. June 18, , Foscarnet - a review of its antiviral activity, pharmacokinetic properties and therapeutic use in immunocompromised patients with cytomegalovirus retinitis.

Chrisp P, Clissold SP. Genital herpes - a guide to pharmacological therapy. Drugs ; 47 2 Deruiter A, Thin RN.

Study summary document link including results : Deruiter A et al Nystagmus secondary to fomepizole administration in a pediatric patient. J Toxicol Clin Toxicol. Childhood methanol ingestion treated with fomepizole and hemodialysis. Study title: Diagnosis, clinical picture and treatment of cytomegaloviral infection in children. Rossiiskii Vestnik Perinatologii i Pediatrii ; 39 3 Diagnosis, clinical picture and treatment of cytomegaloviral infection in children.

Study summary document link including results : Bendel A et al Study summary document link including results : Ding H et al Tolerability of treatments for postherpetic neuralgia [Review]. Drug Safety ; 27 15 Study summary document link including results : Douglas MW et al Advances in antiviral therapy. Current Opinion in Pediatrics ; 9 1 Study summary document link including results : Dwyer DE et al Severe cytomegalovirus infection in immunocompetent patients.

Clinical Infectious Diseases ; 24 1 Study summary document link including results : Eddleston M et al Study title: Open clinical studies with Gd-DTPA dimeglumine gadopentetate in cerebral and spinal diseases - Summary of studies at 22 hospitals. Study title: Open clinical study in dynamic MRI in rheumatic arthritis and related disease. Study title: Open label study of Gadopentetate Dimeglumine as a magnetic resonance imaging MRI contrast agent in pediatric patients presenting with symptoms of central nervous system CNS lesions.

Study title: Open label study of Gadopentetate Dimeglumine as an MRI contrast agent in pediatric patients presenting with symptoms of central nervous system lesions. Study title: Open-Label Study of Gadopentetate Dimeglumine as an magnetic resonance imaging MRI contrast agent in pediatric patients presenting with symptoms of central nervous system lesions. Study title: Time resolved contrast enhanced MR angiography of the hand with parallel imaging and view sharing: initial experience; Brauck K; Eur. Study title: Prospective, multicenter, observational study to document therapeutic data relating to the treatment of Galium-Heel drops [AWB].

Study title: Pharmacokinetics and tolerability of i. Study title: Safety and pharmacokinetics of i. Study title: Prospective, multicenter, reference-controlled observational study for the documentation of therapeutic efficay and tolerability in the use of Gastricumeel tablets or proton pump inhibitors in the treatment of gastritis or heartburn [AWB]. The antipyretic use of acetaminophen versus ibuprofen in a pediatric care setting.

Study title: Report on a comparative assessment of the anti-pyretic activity of Ibuprofen and Paracetamol suspensions in children.

Author's note

Study title: Roth RP et al. Nasal decongestant activity of pseudoephedrine. Ann Otol Rhinol Laryngol ; 86 2 pt. Study title: Single parallel group study investigating the antipyretic properties of ibuprofen syrup vs acetylsalicylic acid syrup in febrile children.

Solinger's Search (Compound Series)

Study title: Single-blind parallel group study investigating the antipyretic properties of Ibuprofen syrup versus Acetylsalicylic acid syrup in febrile children. Study summary document link including results : Ibuprofen-MS Study title: single-dose open study comparing Ibuprofen suspension and Paracetamol suspension in symptomatic therapy of juvenile pyrexia. Study title: Sperber SJ et al. Effectiveness of pseudoephedrine plus acetaminophen for treatment of symptoms attributed to the paranasal sinuses associated with the common cold. Arch Fam Med ; 9 10 Study title: St.

Charles CS et al. Ibuprofen as an antipyretic drug in childhood. Study title: Study 1 - Ibuprofen in the treatment of postoperative pain in small children. A randomised double-blind-placebo controlled parallel group study. Study title: Study of the efficacy and tolerance of Ibuprofen on hectic fever in systemic juvenile chronic arthritis JCA. Antiviral therapy in children with varicella zoster virus and herpes simplex virus infections. Herpes ; 10 2 Enright AM, Prober C. Study summary document link including results : Enright AM et al European-Journal-of- Dermatology ; 5 3 Study summary document link including results : Franca IE et al Acyclovir-resistant herpes simplex virus pneumonia post-unrelated stem cell transplantation: a word of caution.

Pediatr Transplant. Study summary document link including results : Frangoul H et al Study title: Freifeld A. The antimicrobial armamentarium. Hematology-Oncology Clinics of North America ; 7 4 Freifeld A. Study summary document link including results : Freifeld A. Phase i-ii trial of foscarnet for prevention of cytomegalovirus infection in autologous and allogeneic marrow transplant recipients.

Journal of Infectious Diseases ; 3 ; 3 Study summary document link including results : Reusser et al Study title: Gershon AA. Gershon AA. Study summary document link including results : Gershon AA Pediatric HIV infection: a primer for pharmacists. Journal of the American Pharmaceutical Association ;36 10 ; Study summary document link including results : Glassner CL et al Study title: Grose C.

Childhood infections with human herpesviruses types 6, 7, and 8. Advances in Pediatric Infectious Diseases ; Grose C. Study summary document link including results : Grose C. Study title: Gross G, Braun D. Results of postmarketing surveillance]. Hautarzt ; 57 1 Gross G, Braun D. Study summary document link including results : Gross G, Braun D Study title: Haas H. Antiviral treatment in chickenpox. Haas H. Study summary document link including results : Haas H. Study title: Rapporto su uno studio non controllato con Kryptocur denominazione sperimentale HOE nel criptorchidismo.

Weight evolution in girls treated for idiopathic central precocious puberty with GnRH analogues. Journal of Pediatric Endocrinology and Metabolism 19 11 pp , Date of Publication: Nov ; 11 Study title: Antoniazzi F, Zamboni G. Central precocious puberty: Current treatment options. Pediatric Drugs ;6 4 ; 4 Antoniazzi F, Zamboni G. Study title: Auxological outcome and time to menarche following long-acting goserelin therapy in girls with central precocious or early puberty.

Clinical Endocrinology ;61 5 Suppl 2 ; 5 Auxological outcome and time to menarche following long-acting goserelin therapy in girls with central precocious or early puberty. Gonadotropin-releasing hormone agonists in the treatment of girls with central precocious puberty. Clinical Obstetrics and Gynecology ; 36 3 Treatment of gonadotropin dependent precocious puberty due to hypothalamic hamartoma with gonadotropin releasing hormone agonist depot.

Archives of Disease in Childhood ; 80 3 Study title: Gonadotropin-releasing hormone analogues for the treatment of endometriosis: long-term follow-up. Gonadotropin-releasing hormone analogues for the treatment of endometriosis: long-term follow-up. Study title: A Phase I study of gemcitabine in children with refractory solid tumours. Study title: A Phase I study of gemcitabine in children with relapsed or refactory leukemia and non-Hodgkin's lymphoma. Study title: Phase III, controlled, open-label, randomized, single-center study to evaluate the safety and immunogenicity using four different vaccination schedules of tick-borne encephalitis TBE - polygeline free vaccine in adolescents and adults.

Study title: Bronchial secretion and serum levels in children with cystic fibrosis treated with gentamicin. Study title: A double blind dose-ranging study of the efficacy and safety of prophylactic BRLA in controlling cytotoxic drug induced nausea and vomiting in paediatric patients with malignant disease. Study title: Physiologic changes induced by theophylline in the treatment of apnea in preterm infants. Study title: Continuation study for the prophylactic use of intravenous BRLA in controlling cytotoxic drug induced nausea and vomiting in paediatric patients with malignant disease.

Study title: Prospective, multicenter, observational study to document therapeutic data relating to treatment with Graphites-Homaccord ampoules [AWB-AT]. Study title: A short notice and intermediateterm control of success after triennial hypersensitation with Graminea Pollen-Depot- Allergoid Allergovit ; Age of patients: Years. Study title: In-vitro determination of Interleukin-5, Interferongamma as well as IgG4 and IgG1 as monitor parameters in correlation with their clinical course during the first 2 years of preseasonal immunotherapy with a grass allergoid Study title: The gas chromatographic determination of 2 4-isobutylphenyl - propionic acid in Brufen suspension - paediatric modified formula.

Study title: Pharmacovigilance of AlphanineSD; affinity purified, solvent detergent treated: An open label study of viral safety in previously untreated subjects with Haemophilia B. Study summary document link including results : 02 ATC synopsis. Study title: Low risk if viral infection after administration of vapor heated factor VII concentrate or factor IX complex in first time recipients of blood components. Study title: Study to determine the safety of virus inactivated factor concentrates in hemophiliacs naive to blood product administration IFSS. Study summary document link including results : 05 ATG full.

Study summary document link including results : 06 IGB full. Antiviral therapeutic efficacy of foscarnet in hepatitis B virus infection. Antiviral Research. Foscarnet salvage therapy for acyclovir-resistant varicella zoster: report of a novel thymidine kinase mutation and review of the literature.

Pediatr Infect Dis J. Study summary document link including results : Hatchette T et al Penile erosions associated with foscarnet therapy in a child. Pediatr Dermatol. Hick RW, Prose N. Study summary document link including results : Hick RW et al Study summary document link including results : Hubacek P et al Study title: Idanpaan H, Aranko K. Miscellaneous antibacterial and antiviral drugs. In: Side effects of drugs. Elsevier Science Publishers. Idanpaan H, Aranko K. Study summary document link including results : Idanpaan H et al Journal-of-Infectious- Diseases ; July : A dose-ranging study of daily maintenance intravenous foscarnet therapy for cytomegalovirus retinitis in AIDS.

Journal of Infectious Diseases ; 2 Study summary document link including results : Jacobson MA et al Study title: Kawamura Y, Yoshikawa T. HHV-6 encephalopathy. Nippon Rinsho. Kawamura Y, Yoshikawa T. Study summary document link including results : Kawamura Y Study title: Keating MR. Antiviral agents.

Mayo-clinic-proceedings ; 67 2 Keating MR. Study summary document link including results : Keating MR et al Efficacy of a monthly compared to 3-monthly depot GnRH analogue goserelin in the treatment of children with central precocious puberty. Hormone Research ; 68 4 Journal of Clinical Endocrinology and Metabolism ; 85 9 Study title: 4A. A report of patients with superficial skin sepsis treated with fucidin cream. An open assessment of Fucidin Cream as a treatment for superficial sepsis Newby.

Study title: A comparison of Fucidin tablets and Flucloxacillin in skin and soft-tissue infections. Study title: A comparison of fusidic acid viscous eye drops and Chloramphenicol eye ointment in acute conjunctivitis. Study title: A comparison of sodium fusidate ointment and mupirocin ointment in superficial skin sepsis. Study title: Prospective, multicenter, observational study to document therapeutic data relating to treatment with Gripp-Heel tablets in children aged up to 11 years old [AWB]. Study title: Prospective, multicenter, observational study to document therapeutic data relating to the treatment of Gripp-Heel tablets [AWB].

Study title: Prospective, multicenter, observational study to document therapeutic data relating to the treatment of Gripp-Heel injection solution [AWB]. Study title: Korppi M et al. Antitussives in the treatment of acute transient cough in children. Acta Paediatr Scand ; 80 10 Korppi M et al. Acta Paediatr Scand ; 80 10 Study title: Lee PCL et al. Antitussive efficacy of dextromethorphan in cough associated with acute upper respiratory tract infection. J Pharm Pharmacol ; 52 9 Evaluation of antitussive agents in man. Vaccines to be combined in the same syringe and administered to healthy infants as three consecutive doses at 2, 3 and 4 months of age.

Study title: Open randomised clinical study to evaluate the immunogenicity and reactogenicity of SB Biologicals' Hib tetanus conjugate vaccine, co-administered with SB Biologicals' DTPa vaccine either mixed in one syringe, or in two separate injections into opposite limbs, to healthy children around two years of age. Study title: Open study to assess the immunogenicity and reactogenicity of a three-dose primary vaccination course against Haemophilus influenzae type b, diphtheria, tetanus, pertussis and hepatitis B in healthy infants at 6, 10 and 14 weeks of age.

Study summary document link including results : 03 IG synopsis. Study title: A dose-ranging study of Ibuprofen syrup in pyrexia in chlidren. Study title: A double blind, single oral dose study, comparing the antipyretic properties of ibuprofen, acetaminophen and placebo in the treatment of pyrexia associated with infectious disease in children.

Study title: A double-blind comparison of Ibuprofen and Paracetamol in juvenile pyrexia. Study title: A double-blind comparison of the safety and efficacy of a single dose of Children's Advil Ibuprofen suspension 10mg. Study summary document link including results : Ibuprofen-WM Study title: A double-blind comparison of the safety and efficacy of a single dose of Children's Advil Ibuprofen uspension 10mg. Study title: A double-blind multicentre, multiple dose, parrallel group study comparing the efficacy of thre dose levels of Ibuprofen versus Acetaminophen in the Treatment of Pyrexia in Children.

Study title: A double-blind placebo controlled study comparing the safety and efficacy of ibuprofen mg sustained release to ibuprofen mg regular release, in the treatment of post-operative dental pain. Study title: A double-blind placebo controlled study comparing the safety and efficacy of ibuprofen mg sustained release to ibuprofen mg regular release, administered every four hours, in the treatment of post-operative dental pain.

Study title: Kimberlin DW. Antiviral therapy for cytomegalovirus infections in pediatric patients. Seminars in Pediatric Infectious Diseases. Kimberlin DW. Study summary document link including results : Kimberlin DW. Prospective study of renal insufficiency after bone marrow transplantation. Pediatric Nephrology. Study summary document link including results : Kist-van Holthe JE et al Antiviral treatment of varicella in adults and immunocompromised hosts adults and children.

Study summary document link including results : Leport C et al Foscarnet for pre-emptive therapy of cmv infection detected by a leukocyte-based nested pcr in allogeneic bone marrow transplant patients. Bone Marrow Transplantation ;18 3 Study summary document link including results : Ljungman P et al Study title: Ljungman P. Seminars in Respiratory Infections ; 10 4 Ljungman P.

Study summary document link including results : Ljungman P Antivirals for cytomegalovirus infection in neonates and infants: focus on pharmacokinetics, formulations, dosing, and adverse events. Paediatr Drugs. Study summary document link including results : Marshall BC et al A randomized, controlled trial comparing ganciclovir to ganciclovir plus foscarnet each at half dose for preemptive therapy of cytomegalovirus infection in transplant recipients.

Journal of Infectious Diseases 8 , Study summary document link including results : Mattes FM et al Active antiviral agents against human cytomegalovirus and their use in pediatrics. Archives de Pediatrie ; 3:Suppls. Mazeron MC, Alain S. Study summary document link including results : Mazeron MC et al Study title: Mindel A. Recent advances in genital herpes. Annals of the Academy of Medicine, Singapore ; 24 4 Mindel A. Study summary document link including results : Mindel A Study title: Long-acting gonadotropin-releasing hormone agonists in the differential diagnosis of male precocious puberty.

Long-acting gonadotropin-releasing hormone agonists in the differential diagnosis of male precocious puberty. The use of GnRH agonists in severe uterine hemorrhages in adolescence caused by congenital aplastic and hypoplastic anemias. Akusherstvo i Ginekologiia ;38 2 Study title: Fucithalmic in external eye infections. Hvidberg Acta Ophthalmologica, vol 65, no 1.

solinger-s-search-compound-series-bookdoc - Google Документи

Study title: Fucithalmic viscous eye drops in superficial eye infections Open non-comparative study. Study title: Fucithalmic, chloramphenicol or no treatment after squint surgery in children: a single blind randomised study. Fr Ophtalmol ; 12 4 : Study title: Fusidic acid versus tobramycin in suspected bacterial conjunctivitis. Study title: Garborg-O, Nyjordet-R. Study title: Garborg-O. Cutaneous staphylococcal infections in children treated by 2 per cent sodium fusidate ointment. Fusidic acid cream in the treatment of impetigo in general practice: double blind randomised placebo controlled trial.

Fusidic acid cream versus placebo in the treatment of impetigo: a double blind placebo controlled randomized trial. Study title: Liddy-N. Intravenous fusidic acid in the newborn. Study title: Gentamycin in the treatment of infections in the premature infant. Study title: Germs of the serratia genus as etiological agents in septicemic syndroms in children. Orsini A. Study title: Intravenous Gentamicin for infections complications in children wth acute leukemia. Infectious Dis. Suppl - Publication in Gentamicin Registration Dossier - -. Study title: Is the primary suture indicated in infected wounds in pediatric surgery?

Is the primary suture indicated in infected wounds in pediatric surgery? Study title: La pharmacocinetique de la gentamicine chez l'adulte et chez des enfants d'ages divers. Welt, 16, 73 : - Publication in Gentamicin Registration Dossier - -. Study title: Perinatal pharmacology of gentamicin. Study title: Pharmacokinetics of gentamicin during peritoneal dialysis in children - Juskon WJ. Study title: Pharmacokinetics of gentamicin in children and adults. Study title: Pharmacologic evaluation of gentamicin in newborn infants. Study title: Serratia marcescens osteomyelitis in an infant.

Study title: Single-dose kanamycin therapy of gonococcal ophthalmia neonatorum. Single-dose kanamycin therapy of gonococcal ophthalmia neonatorum. Study title: Study of a new antibiotic: injectable gentamicin therapy in paediatrics. Mechanics and energetics of breathing helium in infants with bronchopulmonary dysplasia. J Pediatr ; Study title: Prospective, multicenter, observational study to document therapeutic data relating to treatment with Hepar compositum ampoules [AWB-AT]. Study title: Clinical features of heparin-induced thrombocytopenia including risk factors for thrombosis - Greinacher A.

Study title: Heparin-induced thrombocytopenia associated thrombosis in pediatric intensive care patients - Schmugge M. Study title: Prospective, bicenter, randomised, placebo-controlled, parallel group comparison trial to investigate the antiphlogistic efficacy and tolerance of a fixed combination of levomenol and heparin Sensicutan ointment in patients with atopic eczema.

CSR Medical, College, India. Study title: Ibuprofen vs paracetamol in soft tissue injuries in children. The safety of ibuprofen suspension in children. Lesko SM. Study title: JAMA. An assessment of the safety of pediatric ibuprofen. A practitioner-based randomized clinical trial. However, with major advances in our understanding of the disease process and with the recent development of new technologies that can be used to assess and quantify the evolution of structural changes in OA accurately, all of the elements to successfully develop new and effective DMOADs are now in place.

It is now just a matter of time before a definitive cure for OA is found. National Center for Biotechnology Information , U. Journal List Arthritis Res Ther v. Arthritis Res Ther. Published online Mar Author information Copyright and License information Disclaimer. Corresponding author. Jean-Pierre Pelletier: ac. This article has been cited by other articles in PMC. Abstract Osteoarthritis OA , the most common of all arthritic conditions, is a social and financial burden to all nations. Introduction Osteoarthritis OA is the most common of the musculoskeletal diseases.

Introduction

Clinical aspects For some time the management of clinical OA has largely relied on symptomatic interventions. Table 1 Interventions that potentially reduce progression of structuralchanges in osteoarthritis. Intra-articular interventions: steroids, viscosupplementation. Open in a separate window. Nonpharmacological and preventative strategies Weight loss and knee structure protection It is well known that persons who are overweight are at high risk for developing OA of the knee as well as hips and hands.

Knee misalignment, obesity and osteotomy Misalignment of the limbs associated with longstanding obesity is typical in OA and may be a predisposing factor for rapidly progressing knee OA. Leptin: a metabolic factor for obesity Recently, our group commented on the role of leptin as a contributing factor in promoting cartilage damage in OA [ 4 ]. Physical activity and the role of muscle strengthening in preventing osteoarthritis Exercise is an effective intervention in OA and is an important component in its prevention.

Menisci and anterior cruciate ligament lesions Unfortunately, knee injuries also occur commonly in sports, limiting field and practice time and performance level. Anterior cruciate ligament injury and knee osteoarthritis The aetiology of injury relates primarily to sports-specific activity, and female athletes are at greater risk for knee injury than are their male counterparts in many sports. Meniscal lesions and osteoarthritis: chicken or egg?

Meniscal structural damage as a manifestation of knee osteoarthritis Meniscal damage has been suggested to be an important part of the overall pathophysiology of knee OA. Meniscal repair: conservative versus radical meniscectomy Englund and colleagues [ 21 ] looked at patients with intact cruciate ligaments who had undergone meniscectomy an average of 16 years earlier and compared them with control individuals.

Subchondral bone oedema and bone resorption Recent studies clearly demonstrated the role of subchondral bone in the pathophysiology of OA [ 23 , 24 ]. Pharmacological therapies As indicated above, the pathophysiological events associated with OA are becoming increasingly understood. Inhibition of cartilage degradation Matrix metalloprotease inhibitors For several decades it has been recognized that matrix metalloproteases MMPs play a role in the pathologic breakdown of the joint extracellular matrix in OA.

Cytokine inhibition Recent evidence has implicated a number of cytokines, particularly IL-1, in the OA process of cartilage destruction. Nutraceuticals: glucosamine sulphate and chondroitin sulphate Glucosamine has been evaluated for its efficacy in relieving the symptoms of OA and for its disease-modifying potential.

Intra-articular treatments: steroids and hyaluronic acid The pain and secondary inflammation in OA can be effectively relieved by intra-articular injection of steroids. Inhibition of subchondral bone remodelling Antiresorptive agents As mentioned above, recent research has highlighted the importance of subchondral bone as a target for therapeutic intervention and disease modification in OA [ 23 , 24 ]. The most attractive therapeutic targets: expectations for the future There is still much to be accomplished in the field of OA, particularly with respect to the discovery of new strategies and treatments that can effectively stop the progression of the disease.

Table 2 The most attractive therapeutic targets for the development ofdisease-modifying osteoarthritis drugs. Targeting synovial inflammation Among the significant structural changes that take place during the development of OA is the presence of synovial inflammation. Other inflammatory mediators Blocking inducible nitric oxide NO is an interesting target in the context of OA for at least two main reasons.

Blocking the cyclo-oxygenase and leukotriene pathways In view of the concept that prostaglandins and leukotrienes have complementary effects in perpetuating the inflammatory process, and that chronic inhibition of COX may lead to a shunt of arachidonic acid metabolism toward the leukotriene pathway, blocking both prostaglandin and leukotriene B 4 production could have synergistic effects and achieve optimal anti-inflammatory activity. Peroxisome proliferator-activated receptor gamma The peroxisome proliferator-activated receptors PPARs are nuclear transcription factors that act as anti-inflammatory agents.

Targeting cartilage destruction One of the primary causes of cartilage degradation lies in the destruction of matrix induced by elevated levels of a number of proteolytic enzymes. Aggrecanases The proteases responsible for the cleavage of aggrecan were designated aggrecanases. Targeting subchondral bone remodelling The ultimate goal in the treatment of OA is to improve or preserve the patient's joint structure by preventing its destruction. Future prospects Pharmacogenomics The rapid development of knowledge in the field of genomics and proteomics has revolutionized the approach to the development of new treatments for diseases.

Gene therapy The current use of gene therapy in the treatment of OA is a result of success in identifying major pathophysiological pathways of the disease process. Conclusion This review summarizes some of the knowledge we have today about the possibility of achieving therapeutic interventions that can modify the natural course of OA. Competing interests The authors declare that they have no competing interests. The effect of body weight on progression of knee osteoarthritis is dependent on alignment.

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